Systemic Modulation of Serotonergic Synapses via Reuptake Blockade or 5HT1A Receptor Antagonism Does Not Alter Perithreshold Taste Sensitivity in Rats
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چکیده
منابع مشابه
Antagonism of the 5-HT(3) receptor does not alter isoflurane MAC in rats.
that can decrease postoperative nausea. This ionophore is a member of the fast ligand-gated receptor superfamily that includes g-aminobutyric acid receptor type A, glycine, and neuronal nicotinic acetylcholine receptors. The function of these latter members of the superfamily is known to be sensitive to volatile anesthetics and, in turn, to influence anesthetic potency. For example, in the pres...
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Serotonin and the 5HT(1A) receptor are expressed in a subset of taste receptor cells, and the 5HT(3) receptor is expressed on afferent fibers innervating taste buds. Exogenous administration of the selective serotonin reuptake inhibitor, paroxetine, has been shown to increase taste sensitivity to stimuli described by humans as sweet and bitter. Serotonergic agonists also decrease food and fluid...
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In our previous work, we routinely observed that a combined cocaine-exercise challenge results in an abnormally rapid muscle glycogen depletion and excessive blood lactacidosis. These phenomena occur simultaneously with a rapid rise in norepinephrine and in the absence of any rise in epinephrine. We postulated that norepinephrine may cause vasoconstriction of the muscle vasculature through acti...
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Serotonergic neurotransmission is involved in controlling arousal levels in humans and other animals. Here, the effects of serotonergic receptor antagonists on the induction and depth of anaesthesia produced by three different general anaesthetics were investigated. Rats were pretreated (i.p.) with either methiothepin (1.5 mg kg(-1)), mianserin (5 mg kg(-1)), ketanserin (7 mg kg(-1)) or saline....
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ژورنال
عنوان ژورنال: Chemical Senses
سال: 2014
ISSN: 0379-864X,1464-3553
DOI: 10.1093/chemse/bju028